new paper in Biology

In this paper, Senior Research Associate Santiago Vilar reports how much the proteome of the SARS-CoV-2 virus has changed over … More

new bioRxiv post

In this preprint that is currently under review, graduate student Nick Kapolka reports the surprising discovery that proton-gated coincidence detection … More

new paper in JBC

A tour de force by graduate student Jacob Rowe using computational predictions and cell-based experimental validation to bring new insights … More

new paper in NRDD

In this piece for Nature Reviews Drug Discovery, Nick Kapolka and I discuss the druggability of the understudied GPCR, hydroxycarboxylic … More

new collaborative paper in BJ

In this collaborative project we provided our extensive expertise on the effect of buried ionizable residues on protein structure-function relationships: … More

new paper in JBC

Genome stability is essential for engineering cell-based devices and reporter systems. With the advent of CRISPR technology, it is now … More