In this paper, Senior Research Associate Santiago Vilar reports how much the proteome of the SARS-CoV-2 virus has changed over … More

In this preprint that is currently under review, graduate student Nick Kapolka reports the surprising discovery that proton-gated coincidence detection … More

In this paper, graduate student Geoff Taghon shows that predictable cholesterol binding sites in GPCRs lack consensus motifs: https://pubmed.ncbi.nlm.nih.gov/33508215/

A tour de force by graduate student Jacob Rowe using computational predictions and cell-based experimental validation to bring new insights … More

In this paper, we contributed to the Zhang lab’s efforts to understand the regulation of mitochondrial respiratory chain complex levels, … More

In this piece for Nature Reviews Drug Discovery, Nick Kapolka and I discuss the druggability of the understudied GPCR, hydroxycarboxylic … More

In this collaborative project we provided our extensive expertise on the effect of buried ionizable residues on protein structure-function relationships: … More

Congratulations to Sofia Perez, an undergraduate at Notre Dame and our SURF student in this year of COVID-19. She was … More

https://bit.ly/3eF0SVS

Genome stability is essential for engineering cell-based devices and reporter systems. With the advent of CRISPR technology, it is now … More