A potentially landmark paper by lead author Nick Kapolka and team has been accepted by PNAS:” Proton-gated coincidence detection is a … More

Congratulations to graduate student @NKapolka who’s abstract “Proton-gated coincidence detection is a common feature of GPCR signaling” has been selected … More

Congrats @Jacob_B_Rowe on receiving a General Travel Award in the Graduate Student category to attend the @ASPET Annual Meeting at … More

In this paper, Senior Research Associate Santiago Vilar reports how much the proteome of the SARS-CoV-2 virus has changed over … More

In this preprint that is currently under review, graduate student Nick Kapolka reports the surprising discovery that proton-gated coincidence detection … More

In this paper, graduate student Geoff Taghon shows that predictable cholesterol binding sites in GPCRs lack consensus motifs: https://pubmed.ncbi.nlm.nih.gov/33508215/

A tour de force by graduate student Jacob Rowe using computational predictions and cell-based experimental validation to bring new insights … More

In this paper, we contributed to the Zhang lab’s efforts to understand the regulation of mitochondrial respiratory chain complex levels, … More

In this piece for Nature Reviews Drug Discovery, Nick Kapolka and I discuss the druggability of the understudied GPCR, hydroxycarboxylic … More

In this collaborative project we provided our extensive expertise on the effect of buried ionizable residues on protein structure-function relationships: … More